I need to search the database depending on the selected checkboxes of the regions, their states as it could be solved

table = commerc fields id, name, brand, region, district, provincia, categoria

I need that when consulting the regions, I bring the records and can select through a checkbox the districts and provinces of the selected regions.

How would the call to my database be?

$consulta_estados_visa = $con->query(
    "SELECT commerce_id, commerce_region, commerce_brand 
     FROM commerc 
     WHERE commerce_brand = 'visa' 
     GROUP BY commerce_region"
);

This is my code for calling the database.
This is how I bring the regions registers

<?php while($row = $consulta_estados_visa->fetch_assoc()) { ?>
<label class="list d-flex">
    <?php echo $row['commerce_region'] ?>
    <input type="checkbox" value="<?php echo $row['commerce_id'] ?>" name="estado[]"
    />
</label>
<?php } ?>